Maturation of Red Blood Cells—Requirement for Vitamin B

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(Cyanocobalamin) and
Folic Acid
Because of the continuing need to replenish red blood
cells, the erythropoietic cells of the bone marrow are
among the most rapidly growing and reproducing cells
in the entire body. Therefore, as would be expected,
their maturation and rate of production are affected
greatly by a person’s nutritional status.
Especially important for final maturation of the red
blood cells are two vitamins,vitamin B12
and folic acid.
Both of these are essential for the synthesis of DNA,
because each in a different way is required for the for-
mation of thymidine triphosphate, one of the essential








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