Investigations to diagnose diabetes mellitus

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Investigations to diagnose diabetes mellitus

1- Blood Glucose Testing:

normal fasting whole blood glucose varies from :60-100 mg/dl

normal fasting plasma blood glucose levels are 10-15% higher beacause the structural components of blood cells are absent, so that more glucose is present per unit volume

Aplasma glucose measurement is more frequently used clinically beacause : they are independent of hematocrit

blood samples may be:

Venous: venous blood samples should be collected in tubes containing sodium fluoride which prevents glycolysis in blood samples that would lower the measured glucose level

capillary: capillary blood samples measure capillary whole blood glucose it is performed using glucometer and it is rapid,easy and reliable method



diagnostic values:
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Fasting plasma glucose level more than 120 mg/dl on two or more separate dayes after an overnight fast

random plasma glucose level more than 200 mg/dl



Oral glucose tolerance test: it is rarely used except for questionable cases: if fasting plasma glucose level is between 110-126mg/dl in suspected cases, fasred overnight



2-Urine Testing

testing of the urine for glucose is performed using sensitive glucose-specific dipstick method

advantage: rapid,convenientand glucose-specific

disadvantage: it is rough guide as rental threshold for glucose more than 180 mg/dl is widely changed and increase whith age







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